Curriculum Vitae

Rodney J. Boatman

8 Osage Trail
Spencerport, NY 14559
Residence: 585-293-3441
Cellular: 585-957-3441
E-mail: rjbtox@rochester.rr.com

Education

Year Degree Subject Institution
1977 Ph.D. Chemistry University of Wisconsion, Madison
1972 B.S. Chemistry University of California, Los Angeles

Employment History








Years Employer Title and Responsibilities
03/86 — Present Eastman Kodak Company
Senior Toxicologist, Health and Environment Laboratories

  • Conducted metabolism (ADME) and toxicokinetic studes. This work required the development of sensitive bioanalytical procedures.
  • Developed and used in-house SAR resources for toxicological hazard assessments including development of structure-searchable databases and use of SAR programs including DEREK/METEOR (Lhasa Ltd, UK) and OncoLogic (US EPA).
  • Prepared hazard information and toxickinetic assessments for the registration of chemical in the US and abroad.
  • Provided professional consultative services to the Eastman Chemical Company as a toxicologist representative to glycol ethers panels of the American Chemistry Council (ACC).
  • Provided consultative expertise (under contract) directly to the ACC for work on high production chemicals under the European HPV/ICCA Program and for the preparation of toxicological reviews (published).
  • Served as Chairman of the Eastman Kodak Company Institutional Animal Care and Use Committee, involving review and approval of all in-house animal testing.
07/79 — 03/86 Eastman Kodak Company
Chemist, Health and Environment Laboratories

  • Developed methods to monitor environmental fate and persistence of organic chemicals.
  • Applied chemical and biological methods to treat waste waters.
  • Conducted biodegradation studies.
  • Supervised daily laboratory activities.

Certification

1987 Diplomate, American Board of Toxicology (Recertified, 1993, 1998, and 2003)

Professional Membership

American Chemical Society

Continuing Education

1988 – 2005 Continuing education courses offered by the Society of Toxicology in diverse topics including: Developmental Toxicity; Toxicokinetic Assessment; Risk Assessment; Toxic Responses in Cells; Carcinogenesis; Hematotoxicity; Renal Toxicity; Genetic Toxicology; Advanced Biochemical Mechanisms; Immunotoxicity; and Neurotoxicology.

2003 Training Session, METEOR^TM^ computer program for predicting mammalian metabolism, sponsored by Lhasa Ltd, UK. Novemebr 18-20, 2003.

2002 Training Session, DEREK^TM^ computer program for predicting toxicity, sponsored by Lhasa Ltd., UK. November 20-22, 2002.

1990 Physiologically-Based Pharmacokinetic Models: Principles and Implementation, sponsored by the Chemical Industry Institute of Toxicology, Research Triangle Park, NC, USA. November 13-15.

Awards

Recipient of a Quality Recognition Award from the Chemical Manufacturers Association in recognition of efforts in authoring two chapters in “Patty’s Industrial Hygiene and Toxicology”. Award dated August 24, 1999.

Recent Presentations

METABOLISM AND DISPOSITION OF [2-^14^C]-2-METHYL-1,3-PROPANEDIOL (MPDiolÒ GLYCOL) IN SPRAGUE-DAWLEY RATS FOLLOWING ORAL GAVAGE ADMINISTRATION’
H.B.M. Lantum, R.J. Boatman, P.J. Deisinger, T.S. Guerin, L.M. Cummings, S. Beach, M.J. Thomas, M.I. Banton, W.D. Faber, and J.C. English
The Toxicologist, 78, No. S-1, 98 (Abstract)
Presented at the Society of Toxicology Meeting, Baltimore, MD (2004)

INTERNATIONAL ACTIVITIES AND INDUSTRY INITIATIVES TO IMPROVE THE GLYCOL ETHER KNOWLEDGE BASE’
R.J. Boatman
Invited Speaker, Presented at the International Scientific Symposium on Health Effects of Glycol Ethers, Paris, October 17-18, 2002.

THE PHARMACOKINETICS OF 3.4-EPOXY-1-BUTENE (EpB) AND BUTADIENE DIEPOXIDE (BDE) FOLLOWING NOSE ONLY INHALATION EXPOSURE IN RATS AND MICE TO EpB’
R.J. Boatman, J.C. English, L.G. Perry, T.S. Hill, and L.M. Taylor
The Toxicologist, 60, No. 1, 1392 (Abstract)
Presented at the Society of Toxicology Meeting, San Francisco, CA (2001).

(see References for complete listing)

Recent Publications

Boatman, R. J. (2005). International industry initiatives to improve the glycol ether health effects knowledge base. Toxicol Lett 156, 39-50.

Boatman, R., Corley, R., Green, T., Klaunig, J., and Udden, M. (2004). Review of studies concerning the tumorigenicity of 2-butoxyethanol in B6C3F1 mice and its relevance for human risk assessment. J Toxicol Environ Health B Crit Rev 7, 385-98.

Boatman, R. J., English, J. C., Guerin, T. S., and Cummings, L. M. (2004). The effect of oxygen tension on the cytotoxicity of hydroquinone and selected hydroquinone metabolites to isolated rat renal proximal tubular cells. Arch Toxicol 78, 443-52.

Deisinger, P. J., and Boatman, R. J. (2004). In vivo metabolism and kinetics of ethylene glycol monobutyl ether and its metabolites, 2-butoxyacetaldehyde and 2-butoxyacetic acid, as measured in blood, liver and forestomach of mice. Xenobiotica 34, 675-85.

Boatman, R. J., English, J. C., Perry, L. G., and Fiorica, L. A. (2000). Covalent protein adducts of hydroquinone in tissues from rats: Identification and quantitation of sulfhydryl-bound forms. Chem Res Toxicol 13, 853-60.

Boatman, R. J., English, J. C., Perry, L. G., and Fiorica, L. A. (2000). Covalent protein adducts of hydroquinone in tissues from rats: Quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. Chem Res Toxicol 13, 861-72.

Boatman, R. J., Perry, L. G., Fiorica, L. A., English, J. C., Kapp, R. W., Jr., Bevan, C., Tyler, T. R., Banton, M. I., and Wright, G. A. (1998). Dermal absorption and pharmacokinetics of isopropanol in the male and female F-344 rat. Drug Metab Dispos 26, 197-202.

(see References for complete listing)